Standing at the forefront of basic biomedical science, a vital segment of research that seeks to comprehend the most fundamental processes of health and disease, MRC member charity The Scripps Research Institute is one of the world’s largest private non-profit medical research organizations.
A team led by The Scripps Research Institute in La Jolla has figured out how a mutation causes especially fast-growing cancers, including some forms of leukemia, lymphoma, glioma and melanoma.
Drugs that could thwart this mutation are already in clinical trials, the researchers said in a study published last week. And knowledge of how this mutation works should help identify patients who might be helped by these experimental medications.
It’s unclear what portion of cancers rely on the mutation, which affects a gene called POT1. But regardless of the percentage, these cancers are particularly worrisome because they’re so aggressive, said Scripps researcher Eros Lazzerini Denchi, senior author of the new study.
Click here to read the full article by Bradley J. Fikes, SD Union Tribune.